About Us- Sunil Chopra
About

DR SUNIL CHOPRA BSc MBBS (UK) FRCP (London and Edinburgh)
Consultant Dermatologist

Date of Birth:
Age: 
Sex:
Nationality:
27th September 1965
49 years
Male
British
 
Educational Qualifications: M.B.B.S, University of London, 1990

 

Degree of Bachelor of Science [Immunology], University College London, 1986

 

Fellow of the Royal College of Physicians (London and Edinburgh), 2012
 
GMC Status: Registered with the General Medical Council (GMC) UK. Full Registration number 3328774
 
Memberships: British Medical Association (BMA)
Royal Society of Medicine (RMS)
British Association of Dermatology (BAD)
 
Prizes: National Amulree Prize for the Care of the Aged, 1989
Primary Health Care Prize 1988
ICI Elective Award 1988
 
Research:

 

Jan 2005 to 2013
London School of Pharmacy
University College London
Investigation and clinical trials of nano liposomal encapsulation of Bleomycin for the topical treatment of Basal cell carcinomas and keloids. Research conducted in collaboration with Professor S Brocchini and Professor Navsaria H.
Feb 2017 to Date
Investigation and clinical trials of nano liposomal encapsulated Bleomycin for the topical treatment of equine sarcoid and tumours in small animals. Skin penetration studies of topical liposomal Bleomycin in large and small animals. Research conducted in collaboration with Professor Derek Knottenbelt (Glasgow University) and Professor David Argyle Dick School of Veterinary Medicine and The Roslin Institute (Edinburgh University).
BSc Project “Role of Tumour Necrosis Factor in immunity to Malaria”.
Undergraduate “Increased General Practitioner consultation rates amongst carers of the elderly.” Prize winning project- National Amulree Prize in care of the elderly.
Postgraduate
August 94-30/09/96
“The Neurovascular pathophysiology of Raynaud’s phenomenon”.
I have used the techniques of quantitative immunohistochemistry and also in-vivo pharmacology to study Raynaud’s phenomenon of different aetiologies. I acquired the necessary skills in immunohistochemistry at the Royal Free Postgraduate Medical School under Professor JM Polak for one year and then established them at UCL. I have also established new techniques in the laboratory and developed an objective test for Vibration White Finger.
Notable Achievements in Dermatology: Clinical Director and Founder of the London Dermatology Centre, Wimpole Street, London WC1, founded 2004.

 

Director and founder of SPS Healthcare. This is a company that specializes in developing drugs for delivery in skin disease. The company owns one granted patent and owns one submitted patent. SPS Healthcare collaborates with the following scientists.
Past Dermatology Teaching Experience: Undergraduate student teaching at Bart’s and the London Medical School.
Barking and Dagenham General Practitioner Skin Club – Bimonthly teaching

 

University College Hospital Accident and Emergency, regular teaching of SHOs and registrars

 

London Dermatology Centre continuing medical education for GPs – Bimonthly teaching

Employment History:
Dermatology Present Appointments: 01/06/01 – Present

Name and Address of Employer Grade and Specialty
London Dermatology Centre, Wimpole Street, London WC1 Clinical Director and Founder
SPS Healthcare, London Director and Founder

Dermatology Previous Appointments

Name and Address of Employer Dates of Employment, Grade and Specialty
Barking and Havering and Redbridge NHS Trust 01/08/01 – 01/09/08
Consultant Dermatologist
Bart’s and The London Hospitals 01/08/01 – 01/09/08
Honorary Consultant Dermatologist
The Royal London Hospitals NHS Trust and Homerton Hospital NHS Trust Senior Clinical Fellow (Post CCST)
Royal London Hospitals NHS 18/10/99-30/09/00
Specialist Registrar in Dermatology
Ealing and Hammersmith Hospitals 01/06/98-17/10/99
Specialist Registrar in Dermatology
Imperial College School of Medicine 01/06/98-17/10/99
Honorary Research Registrar
UCL Hospitals NHS Trust 01/10/96-30/05/98
Specialist Registrar in Dermatology
University College London Medical School 01/08/94-30/09/96*
Research Registrar and Honorary Clinical Registrar in Dermatology to PM Dowd
Middlesex Hospital. 01/02/93- 30/09/93
Senior House Officer in Dermatology to Drs TWE Robinson, JJH Gilkes, GM Levene and PM Dowd
Chase Farm Hospital, Enfield 01/12/91-31/07/92
Senior House Officer in Dermatology to Dr Almeyda

*Further Details:
UCL Hospitals NHS Trust - 01/10/96-30/05/98 - Specialist Registrar in Dermatology

1994 thesis entitled "The neurovascular pathophysiology of Raynaud's phenomenon". This involved clinically assessing 27 vibration exposed workers; on site at a British shipyard; for vibration white finger. Each subject’s cutaneous digital vascular responses to injected neuropeptides were assessed using planimetry and laser Doppler flow measurements. All subjects underwent digital cutaneous biopsy and immunostaining for neurovascular peptides. All of the above procedures were carried out on 6 patients with acrocyanosis and perniosis, 6 patients with Raynaud’s phenomenon associated with systemic sclerosis and 6 patients with primary Raynaud’s phenomenon.

The post also involved lecturing medical students, chiropodists, general practitioners and postgraduate students studying for the MRCP part II. I was one of the examiners for the MBBS Jenner Living Dermatology prize and project examiner to the London Foot Hospital. The clinical responsibilities involved one specialist cold related disorders clinic and cover for sick leave for the consultants.

General Medicine Previous Appointments

Name and Address of Employer Dates of Employment, Grade and Specialty
Addenbrookes Hospital, Cambridge 01/11/93-01/02/94
Registrar in Chest Medicine and Intensive Care to Dr T W Higgenbottam and Dr G Park
Papworth Hospital, Cambridge 01/03/94-31/07/94
Registrar in Chest Medicine to Dr J M Schneerson
Middlesex Hospital 01/02/93-01/08/93
Senior House Officer in Dermatology and General Medicine
Middlesex Hospital 01/8/92-31/01/93
Senior House Officer in HIV and Genitourinary Medicine
Chase Farm and Highlands Hospital 01/08/91-31/07/92
Senior House Officer Rotation in General Medicine
Royal Free Hospital 01/02/91-31/07/91
Senior House Officer in Accident and Emergency and Intensive Care
University College Hospital 01/11/90-31/01/91
House Physician to M.D.R Sarner and Professor S.G. Bown
Middlesex Hospital 01/08/90-31/10/90
House Physician to A.M Cassoni and M Coulter
Ipswich General Hospital 01/02/90-31/07/90
House Surgeon to I.H.K. Scott
 
Patents: Patent Granted: Patent Number: GB2398495
“A drug delivery preparation comprising at least one anti-tumour drug and a topical carrier for the drug” S Chopra and K Lau. 22 Aug 2007

Patent Submitted: Patent filed 2007. Under Review
“A topical stable flexible liposomal drug delivery system encapsulating bleomycin” S Chopra.
 
Publications: ‘Dermatological problems’ S Chopra, M Knight, and F Vega Lopez Manson’s 22nd Edition ‘Textbook of Infectious Disease’ 2009

Br J Dermatol. 2008 Sep; 159(3): 628-32. ‘Treatment of rosacea with intense pulsed light: significant improvement and long-lasting results’. Papageorgiou P, Clayton W, Norwood S, Chopra S, Rustin M.

 

Phenotypic and clinical differences between Caucasian and South Asian patients with psoriatic arthritis living in North-East London. Euthalia Roussou, Sunil Chopra* Danny Lunda Ngandu**In Press Clinical Rheumatology 2013

E. T. Anthony, S. Kantaria, G. C. Moir and S. Chopra. ‘The penetrative abilities of liposomal in explanted keloids’ Clin Exp Dermatol. 2009 Apr; 34 (3): 408-9

 

Kuttikat A, Saeed T, Chopra B, Chopra S, Chakravarty K. ‘Nasal Wegener's and skin sarcoid--a rare combination of two granulomatous diseases’. Clin Rheumatol. 2006 Nov; 25(6): 895-7.

 

Berth-Jones J, Arkwright PD, Marasovic D, Savani N, Aldridge CR, Leech SN, Morgan C, Clark SM, Ogilvie S, Chopra S, Harper JI, Smith CH, Rook GA, Friedmann PS. ‘Killed Mycobacterium vaccae suspension in children with moderate-to-severe atopic dermatitis: a randomized, double-blind, placebo-controlled trial’. Clin Exp Allergy. 2006 Sep;36(9):1115-21

 

Anthony E, Syed M, Vaiude P, Chopra S, Davies K, Nduka C, Shibu M, Moir GC. ‘A 6 year review of the clinical relevance of steroid therapy in keloid management’. International Proceedings of the 7th European Trauma Congress. May 2006.

 

Kuttikat A, Saeed T, Chopra B, Chopra S, Chakravarty K. Nasal Wegener's and skin sarcoid-a rare combination of two granulomatous diseases. Clin Rheumatol 2005:1-3

 

Lau KG, Hattori Y, Chopra S, O'Toole EA, Storey A, Nagai T, et al. ‘Ultra-deformable liposomes containing bleomycin: in vitro stability and toxicity on human cutaneous keratinocyte cell lines’. Int J Pharm 2005;300(1-2):4-12

S Chopra, F Jabber, S Pereira. ‘Anticonvulsant hypersensitivity disorder’. Journal of Psychiatric Intensive Care. Vol 1. 2:117-120. 2005

‘Dermatological problems’ F Vega-Lopez and S. Chopra. Manson’s 21stth Edition ‘Textbook of Infectious Disease’ 2003

S. Chopra and A.C Chu. “Treatment of Cancer” Eds Pat Price and Karol Sikora. 4th Edition. Arnold 2002. Chapter 38 ‘Non-Melanoma Skin Cancer’. PP 799-830

Clin Exp Dermatol. 2001 Sep; 26(6):510-2 ‘Erythema gyratum repens and acquired ichthyosis associated with transitional cell carcinoma of the kidney.’
Ameen M, Chopra S, Darvay A, Acland K, Chu AC.

S. Chopra, P.Human and A.C Chu. ‘Antihistamines in atopic dermatitis’. CME Bulletin Dermatology.1999 (2); 1, 16-19.

Pauline M Dowd, P. Goldsmith, S. Chopra, H.A Bull and JC Foreman. ‘Cutaneous responses to endothelin-1 and histamine in patients with vibration white finger’. J Invest Dermatol. 1999 Feb; 110(2): 127-31

S. Chopra, S.Munn and A.C Chu. ‘B-cell lymphoma presenting as Langerhans cell histiocytosis. BAD proceedings’ Br J of Dermatol. 1999, 141 supplement 55. 128

S. Chopra and F Vega-Lopez. “The Granulomatous disorders” Eds: D.Geraint James and Alimuddin Zumla. Cambridge University Press 1999. Chapter 33-Skin Granulomas in Clinical Practice. PP 485-525

Bull HA, Leslie TA, Chopra S, Dowd PM. ‘Expression of nerve growth factor receptors in cutaneous inflammation’. Br J Dermatol 1998;139(5):776-83

S. Chopra, N.J. Levell, G. Cowley and J.J.H. Gilkes. ‘Systemic Corticosteroids in the phenytoin hypersensitivity syndrome’. Br J of Dermatol 1996; 134: 1109-1112.

S. Chopra, M.M.L Martins and PM. Dowd. ‘Increased expression of nerve growth factor, p75 nerve growth factor receptor and GAP 43 in systemic sclerosis’: BSID proceedings. Br J of Dermatol 1996; 134: 592.

S. Chopra, M.M.L Martins and P. M. Dowd. ‘Comparison of the expression of nerve growth factor, p75 nerve growth factor receptor, trk A and GAP 43 in systemic sclerosis and vibration white finger’ SID proceedings J Invest Dermatol 1996, 106: 821.

N.J Levell, A.P. Bewley, S. Chopra, D. Churchill, P. French, R. Miller and J.J.H. Gilkes. ‘Bacillary angiomatosis with cutaneous and oral lesions in an HIV-infected patient from the U.K.’ Br J of Dermatol 1995; 132: 113-115.

S. Chopra, H. A. Bull and Pauline M. Dowd. ‘Nerve Growth Factor and its receptors in relation to GAP 43 and cutaneous nerve fibre depletion in Vibration White Finger’. In preparation.

S. Chopra, H.A Bull & Pauline M. Dowd. Nerve Growth Factor & its receptor p75 & GAP 43 are upregulated in the Raynaud’s phenomenon of Systemic sclerosis but not in Primary Raynaud’s phenomenon. In preparation.
 
Postgraduate Book Chapter: ‘Dermatological problems’ S Chopra, M Knight, and F Vega Lopez Manson’s 22nd Edition ‘Textbook of Infectious Disease’ 2009
  ‘Dermatological problems’ F Vega-Lopez and S. Chopra. Manson’s 21stth Edition ‘Textbook of Infectious Disease’ 2003

S. Chopra and A.C Chu. “Treatment of Cancer” Eds Pat Price and Karol Sikora. 4th Edition. Arnold 2002. Chapter 38 ‘Non-Melanoma Skin Cancer’. PP 799-830

S. Chopra and F Vega-Lopez. “The Granulomatous disorders” Eds: D.Geraint James and Alimuddin Zumla. Cambridge University Press 1999. Chapter 33-Skin Granulomas in Clinical Practice. PP 485-525
Presentations at International conferences: September 2011- A Novel Typical Liposomal Encapsulated Bleomycin Formulation for use against Basal cell carcinoma and treatment resistant wart s and verrucae. Elizabeth Blakely, Shilpa Kanteria, Manuchehr Porssa, Graham Moir, Lina Christopoulou, Fatima Malik, David McCarthy and Sunil Chopra. ESDR Meeting 7-10 September 2011, Barcelona , Spain

A Novel stable form of Kojic Acid to treat pigmentation problems. Sunil Chopra (1)(2), Fatima Malik ( 2), Shilpa Kantaria (3) Art Tucker (4) 1- University College London 2- London Dermatology Centre, 3- London School of Pharmacy, 4- Bart’s and the London Medical School. Japanese Dermatological Association and Australian College of Dermatologists. 2009 Hokkaido, Japan

October 2009- A novel stable form of liposomal bleomycin for use in actinic keratosis and basal cell carcinoma F Malik, S Kantaria , S Davison , S Chopra European Academy Of Dermatology and Venerology Berlin 2009

Preliminary results treating primary nasal bcc with topical liposomal bleomycin Authors: Eva Papesch; Sunil Chopra area: Oncology and Head and Neck Surgery ENT World Congress - IFOS 2009 Brazil

A.C. Chu, S. Chopra and M Amheen. Calipitriol in vitiligo an open study. European Academy of Dermatology and Veneorology- Amsterdam, 29 September-4 October 1999

S.Datta, S. Chopra and PM Dowd. Vascular hyporeactivity in acrocyanosis and perniosis. American Academy of Dermatology Annual Conference May 23-28 1999-Chicago

H. A. Bull, S. Chopra, PM. Dowd. Nerve Growth Factor and its receptors and GAP 43 in cutaneous inflammation and vasospasm. 55th Annual Meeting of American Academy of Dermatology, 21-26th March 1997 - San Francisco.

S. Chopra, H. A. Bull and Pauline M. Dowd. Diltiazem therapy partially reverses the cutaneous nerve fibre depletion of Vibration White Finger. 25th Anniversary Meeting European Society for Dermatological Research, 28th September-1st October 1996 – Amsterdam

S. Chopra, M.M.L. Martins and P.M. Dowd. Comparison of the expression of nerve growth factor, p75 nerve growth factor receptor, trk A and GAP 43 in systemic sclerosis and vibration white finger. Society of Investigative Dermatology, 1-5th May 1996 - Washington DC.

H. A. Bull, S. Chopra and Pauline M Dowd. Neuropeptides, Vasospasm and cutaneous inflammation.
45th Annual Symposium on the biology of skin, 20-24th May 1996 - Snowmass, Colorado

Anthony ET, Vaiude PN, Syed M, Chopra S, Rattan B, Navsaria H The use of skin explants and primary cells in testing nano liposomal topical keloid treatments; Tissue Engineering, Wurzburg, Germany May 2006

Anthony ET, Vaiude PN, Chopra S, Syed M, Rattan B, Leigh I, Navsaria H. Treatment of keloids with liposomes. Scars 2006, Montpellier, France 29 March 2006
National: Anthony ET, Vaiude PN, Syed M, Chopra S, Navsaria H; Nano-liposomal Bleomycin: The future for BCC treatment; Brit Assoc of Plastic Surgery summer meeting, Sheffield; 12 July 2006– Poster

Anthony ET, Chopra S, Moir GC, Navsaria HN. Emerging Nano-liposomal technology for BCC treatment. West Midlands National Plastics and Burns Surgery Meeting; October 2005

S. Chopra, S. Munn and A.C. Chu. B-cell lymphoma presenting as Langerhans cell histiocytosis. British Association of Dermatology 79th Annual Meeting, 29 June – 3 July 1999- Edinburgh

S. Chopra, V. Exarchou and A.C. Chu. Digital videomicroscopy in the follow up of pigmented skin lesions. British Association of Dermatology 79th Annual Meeting, 29 June – 3 July 1999- Edinburgh

S. Chopra, M.M.L Martins and Pauline M. Dowd. Increased expression of nerve growth factor, p75 nerve growth receptor and GAP 43 in systemic sclerosis. British Society of Investigative Dermatology, 28 -29th March 1996 – Glasgow
University Poster Presentation: Anthony ET, Lau K, Trigiante G, Chopra S, Moir GC, Navsaria HN. Bleomycin in an Ultra Deformable Liposome. William Harvey Day, Great Hall, St Bartholomew’s Hospital, Queen Mary, University of London; October 2005
Presentations at Royal Society of Medicine Section of Dermatology: S. Chopra and A.C Chu. CD30+ lymphoma occurring in a patient with a diagnosis of psoriasis. November 1999

S. Chopra and R. Russell Jones. Cutaneous vasculitis and hepatitis C infection. February 1999

S. Chopra and N.J Lowe Transplacental transfer of antityrosinase IgG antibody causing vitiligo in a newborn baby. March 1998

S. Chopra and R.Groves. A case of hereditary anetoderma. March 1998

S. Chopra and R.Y Yu. Vesicular eruption in a case of Churg Strauss vasculitis CPC. January 1998

S. Chopra and P.M Dowd. Primary erthromelalgia. 17th April 1997

S. Chopra and R.Y Yu. Spontaneous graft versus host disease 17th April 1997

S. Chopra and J.J.H. Gilkes. Phenytoin hypersensitivity syndrome. 15th June 1995
Presentations at Grand Rounds: B-Cell Lymphoma presenting as Langerhans histiocytosis. Hammersmith Hospital, July 1999

Bullous pemphigoid associated with malignancy. Hammersmith Hospital, April 1999

Churg Strauss syndrome presenting as blindness. Hammersmith Hospital, February 1999

Phenytoin hypersensitivity syndrome. Hammersmith Hospital, July 1998

Primary erythromelalgia. UCL Hospitals, February 1998

Epidermodysplasia verruciformis. UCL Hospitals, November 1997
St John’s Registrar meetings: Presented on 2 occasions - October 1998 and June 1999
Courses Organised: UCL Hospitals NHS Trust – Annual Teaching Course for general practitioners – lectured on two occasions

Hammersmith Hospitals NHS Trust – Annual Practice Nurses Course – lectured on two occasions.
Courses Attended: Hammersmith Hospitals Skin Histopathology Course – May 1999

 

Novartis Management Course – February 1998

 

Skin Biology Course – Cambridge 1996
Medical School Activities: Elected the first University College and Middlesex School of Medicine Students Union president 1986-87

 

 

Affiliations
The London Dermatology Centre is run by leading dermatologists and plastic surgery consultants from major London teaching hospitals and regional centres of excellence.